WebHDAg is encoded as two isoforms within a segment of the HDV genome, namely the small HDAg (S-HDAg, 195 aa, 24 kDa) and the large HDAg (L-HDAg, 214 aa, 27 kDa). While S-HDAg is necessary to initiate and maintain replication, L-HDAg negatively regulates replication and triggers envelopment of the virus into the HBV surface proteins. WebHDAg binds specifically to the HDV RNA and occurs in two different forms: the small HDAg (S-HDAg, 24 kDa) is important for virus replication, whereas the large variant (L-HDAg, 27 kDa) inhibits replication and promotes virus assembly ( …
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Auf dem Wellgetriebeprinzip basierende Präzisions-Antriebstechnik der Marke Harmonic Drive® finden Sie im Werkzeugmaschinenbau ebenso selbstverständlich wie in der Robotik, der Luft- und Raumfahrt und zahlreichen anderen Schlüsselindustrien. WebHDV encodes a single protein, HDAg, which was the nuclear antigen originally detected by Mario Rizzetto. HDAg is not exposed on the virion surface; rather, it can be detected only after the virus envelope is disrupted. The protein consists of two species, small HDAg (24 kDa, 195 amino acids) and large HDAg (27 kDa, 214 amino acids). pinebank arch bridge
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