WebNov 24, 1998 · The fluoroolefin dipeptide isostere was proposed as early as 1984 ( 51) as a superior isoelectronic and isosteric replacement for the amide bond. Theoretical studies strongly have supported the original hypothesis behind introduction of the fluoroolefin amide surrogate ( 52 – 54 ). WebFrom the experimental polarizability values, alpha, of a large set of solvents containing 426 compounds with very different chemical characteristics, an additive model for the estimation of the polarizability is proposed. The derived average atomic polarizability of 10 elements, C, H, O, N, S, P, F, …
Inhibition of dipeptidyl peptidase IV by fluoroolefin-containing
WebS>The polymerization of a number of fluoro-olefines was studied by irradiating with Co/sup 60/ gamma rays in bulk'' at 20 to 25 deg C. The polymerization of 2,3,3,3-tetrafluoropropene-1 went most readily with a radiation yield of 350 molecules/ 100 ev (based on the consumption of monomer). WebJul 28, 2024 · Synthesis of fluoroolefin derivatives by nickel (ii)-catalyzed trifluorovinylation and 1,2,2-trifluoroethylation of cinnamyl alcohols - Organic & Biomolecular Chemistry … can sweet peas grow in pots
Chiral dipeptide mimics possessing a fluoroolefin moiety: a …
WebJan 1, 2008 · Fluoroolefins as one of the best amide bond replacements In 1984, the fluoroolefin ψ [CF=CH] isostere ( 3b) ( Fig. 3) was first proposed as a superior … WebApr 1, 2024 · The manuscript reports the synthesis, characterization, and analysis of electronic structure in a series of complexes of small perfluorocarbon ligands with the (PNP)Rh fragment (where PNP is a diarylamido/bis (phosphine) pincer ligand). WebJan 29, 2008 · The synthesis, selectivity, rat pharmacokinetic profile, and drug metabolism profiles of a series of potent fluoroolefin-derived DPP-4 inhibitors (4) are reported. A … flashback 6