WebNov 29, 2024 · Also in the literature, urine cytology for UCB and UTUC is known to have a lower sensitivity at a comparable or higher specificity than FISH [4, 13–16]. But, especially for low-grade urothelial carcinoma, the diagnostic yield of urine cytology is limited . This hampers the suitability of standard cytological assessment as a triage test for ... WebApr 16, 2024 · The use of urine cytology involves the microscopic evaluation of voided urine or bladder-washes for exfoliated cancer cells. Although it has historically been reported to have a high sensitivity ...
Urine Cytology - an overview ScienceDirect Topics
http://mdedge.ma1.medscape.com/hematology-oncology/article/191645/genitourinary-cancer/mrna-based-urine-test-performs-well-bladder WebVysis UroVysion is a molecular cytology test that detects aneuploidy of chromosomes 3, 7, and 17 and deletion of the 9p21 locus via fluorescence in situ hybridization (FISH) in urine specimens. In a study of 497 patients with hematuria, the Vysis UroVysion test showed a diagnostic sensitivity of 69% and specificity of 78% compared with ... cylindrical packaging boxes
Fluorescence in situ hybridization (FISH) in the diagnosis of ... - PubMed
WebLow-grade UCs are detected less reliably by cytology, as compared to high-grade UCs. 34, 35, 39-41 Finally, the sensitivity of urine cytology is reduced in patients who have been treated with radiation or chemotherapy. 35 Molecular cytogenetic analysis using the fluorescence in situ hybridization (FISH) method shows promise in improving on the ... Weburine cytology to detect recurrent UC.12A total of 100 patients with a history of bladder cancer submitted a single voided urine sample, immediately followed by cystoscopy and biopsy. o The overall results of sensitivity for low- and high-grade UC for the various tests were as follows: Cytology, 15% and 27%; Immunocyt, 62% and 91%; and WebFISH hypertetrasomy showed sensitivity and specificity for diagnosis of upper tract carcinoma of 50% and 89%, ... Urine cytology as a method for diagnosing bladder carcinoma was introduced in 1945 by Papanicolaou and Marshall. 1 Urothelial cells are present in all urine specimens and exfoliate readily from tumors of the urothelial lining. cylindrical packaging