WebApr 9, 2024 · Because AIM2 does not discriminate between host and microbial dsDNA, it is widely believed that activation of AIM2 inflammasome underlies the pathogenesis of many auto-inflammatory diseases (Kumari et al., 2024).In support of this notion, AIM2, along with other inflammasome components, has been shown to play a pathogenic role in various … WebDec 9, 2024 · AIM2 is known to play a role in the host immune response to microbial DNA ; however, several reports have established that endogenous double-stranded DNA (dsDNA) can also activate AIM2 to form the ...
Regulation of inflammasome activation - PubMed
WebFeb 20, 2024 · Background AIM2, a cytosolic DNA sensor, plays an important role during infection caused by pathogens with double-stranded DNA; however, its role in human cytomegalovirus (HCMV) infection remains unclear. Previously, we showed an increase in AIM2 protein levels during the early stage of HCMV infection and a decrease 24 h post … WebPolyclonal Antibody for studying AIM2. Cited in 3 publications. Validated for Western Blotting. Highly specific and rigorously validated in-house, AIM2 Antibody (CST #8055) is ready to ship. birch hill bed \u0026 breakfast sheffield ma 01257
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WebPolyclonal Antibody for studying AIM2 mouse. Cited in 13 publications. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously validated in-house, AIM2 Antibody (Mouse Specific) (CST … WebBackground. Absent in melanoma 2 (AIM2) is an interferon-inducible protein containing an amino-terminal pyrin domain and carboxy-terminal HIN-200 domain that functions in innate immunity and tumor progression (1). … WebAug 16, 2024 · A command-and-control (C2) server is a main tool cyber threat actors have in their arsenal to launch and control cyber attacks. Threat actors use C2s to send … dallas extended forecast weather