WebMar 28, 2013 · Nephrotic syndrome results in profound alteration of lipid metabolism and plasma lipid profile. Genes encoding enzymes involved in fatty acid synthesis are independently regulated by SREBP-1c, LXRα/β and ChREBP [30,31]. The present study revealed significant upregulation of FAS and ACC, the key enzymes in fatty acid … WebFeb 1, 2024 · The observation that ChREBP-deficient mice are intolerant to diets containing fructose but not to diets containing dextrose suggests a specific role for ChREBP in regulating fructose metabolism (37, 133). Moreover, ChREBP activity was markedly higher in rats fed high-fructose compared with isocaloric high-glucose diets .
Adaptive and maladaptive roles for ChREBP in the liver and …
WebMar 19, 2024 · First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic … WebJan 17, 2024 · ChREBP activates metabolic gene expression. This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped … canada jetlines stock
ChREBP, a Transcriptional Regulator of Glucose and Lipid …
WebJul 30, 2024 · ChREBP is a glucose-responsive transcription factor, which regulates glucose-mediated proliferation and cell death in pancreatic β-cells. Here the authors … WebOct 15, 2009 · Carbohydrate-responsive element-binding protein (ChREBP) is a transcription factor that has been shown to regulate carbohydrate metabolism in the liver … WebAccredited CHRP Training Institutions – HRMPEB. Request Call Back +254 799 016630. Monday - Friday 8AM - 5PM. Mwalimu Towers 1st Floor. canada jetlines ltd stock