Biological applications of ionophores
WebAug 13, 2024 · Labile zinc, a tiny fraction of total intracellular zinc that is loosely bound to proteins and easily interchangeable, modulates the activity of numerous signaling and … WebNov 1, 2024 · Copper ionophores alter the concentration, distribution, and reactivity of endogenous copper ions with consequent profound biological repercussions. The …
Biological applications of ionophores
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WebApr 13, 2024 · Matthew Songer, (Biological Sciences ’79) and Laura Songer (Biological Sciences ’80) have generously donated funds to the College of Sciences and Arts (CSA) … WebApr 6, 2024 · Ionophores transport ions across biological membranes and have wide-ranging applications, but a platform for their rapid development does not exist. We report a platform for developing ionophores from metal-ion chelators, which are readily available with wide-ranging affinities and specificities, and structural data that can aid rational design.
WebMar 4, 2024 · The development of new therapeutic agents should aim to increase selectivity and therefore reduce side effects. In addition, these agents should overcome cancer cell resistance and target cancer ... WebBiological applications of ionophores. Pressman BC. Annual Review of Biochemistry , 01 Jan 1976, 45: 501-530 DOI: 10.1146 ... Biological applications and evolutionary origins of ionophores. Pressman BC, deGuzman NT. Adv Exp Med Biol, 84:285-300, 01 Jan 1977
WebJan 24, 2024 · DNA based ionophores can mediate efficient ion transport and are crucial to understand the biological role of their natural counterparts. Here authors engineer a telomeric DNA G-quadruplex based ... WebDec 21, 2024 · Zinc ionophores increase the intracellular concentration of Zinc ions causing significant biological effects. This review provides, for the first time, an overview of the …
WebAbstract. Ionophores are substances which facilitate the movement of ions into and/or through organic phases. The two major classes of compounds are the neutral ionophores, which form charged clathrate complexes with ions, and the carboxylic polyether ionophores which are neutral in the complexed state. Many of the ionophores exclusively bind ...
WebIonophores are compounds that form lipid soluble, dynamically reversible complexes with cations and by this means facilitate specific ionic transport across biologic membranes (Pressman, 1976; Reed, 1982; Taylor et al., 1982 ). There are two major subclasses of ionophores, (1) neutral ionophores, which are highly toxic because they form charged ... bingo world baltimore january calendarWebBiological applications of ionophores. by B C Pressman. Annual review of biochemistry. Read more related scholarly scientific articles and abstracts. d4s 35w bulbWebAnalogous ionophores have now been synthesized. Unique applications for these compounds are emerging, based either on their selective toxicity or ability to modify … d4s 55wWebMay 30, 2013 · Moreover, the discovery of salinomycin and other natural ionophores as CSC-selective drugs opened up the possibility of repurposing these drugs for novel applications in human medicine ... bingo world cape girardeau moWebThe Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous … d4 sacred itemsWebMay 27, 2024 · Despite several ionophores revealing potential therapeutic applications as apoptosis inducers, ... In the context of transporting molecules of biological relevance, quite a few ionophores have been … d4 scythe\u0027sWebJul 1, 1976 · Ionophores are compounds of moderate molecular weight (about 200-2(00) that form lipid-soluble complexes with polar cations, of which K+, Na+, Ca2+, Mg2+, and … bingoworld charlottetown